STEM CELLS IN HEMATOLOGY Self-renewal of human embryonic stem cells requires insulin-like growth factor-1 receptor and ERBB2 receptor signaling
نویسندگان
چکیده
1Division of Hematology, Department of Medicine, Institute for Stem Cell and Regenerative Medicine, University of Washington, Seattle; 2Novocell, Athens, GA; 3Invitrogen, Carlsbad, CA; 4Department of Comparative Medicine, University of Washington, Seattle; 5Division of Medical Genetics, Department of Medicine, University of Washington, Seattle; 6Department of Animal and Dairy Science, University of Georgia, Athens; 7Department of Pathology, College of Veterinary Medicine, University of Georgia, Athens; and 8Novocell, San Diego, CA
منابع مشابه
Self-renewal of human embryonic stem cells requires insulin-like growth factor-1 receptor and ERBB2 receptor signaling.
Despite progress in developing defined conditions for human embryonic stem cell (hESC) cultures, little is known about the cell-surface receptors that are activated under conditions supportive of hESC self-renewal. A simultaneous interrogation of 42 receptor tyrosine kinases (RTKs) in hESCs following stimulation with mouse embryonic fibroblast (MEF) conditioned medium (CM) revealed rapid and pr...
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تاریخ انتشار 2007